Oxygen therapy, also known as supplemental oxygen, is the use of oxygen as a medical treatment. This can include for low blood oxygen, carbon monoxide toxicity, cluster headaches, and to maintain enough oxygen while inhaled anesthetics are given. Long term oxygen is often useful in people with chronically low oxygen such as from severe COPD or cystic fibrosis. Oxygen can be given in a number of ways including nasal cannula, face mask, and inside a hyperbaric chamber.

Oxygen is required for normal cell metabolism. Excessively high concentrations can cause oxygen toxicity such as lung damage or result in respiratory failure in those who are predisposed. Higher oxygen concentrations also increase the risk of fires, particularly while smoking, and without humidification can also dry out the nose. The target oxygen saturation recommended depends on the condition being treated. In most conditions a saturation of 94-98% is recommended, while in those at risk of carbon dioxide retention saturations of 88-92% are preferred, and in those with carbon monoxide toxicity or cardiac arrest they should be as high as possible. Air is typically 21% oxygen by volume while oxygen therapy increases this by some amount up to 100%.

The use of oxygen in medicine become common around 1917. It is on the World Health Organization's List of Essential Medicines, the most effective and safe medicines needed in a health system.

Adult: Use as required
Child: Safety and efficacy has not been established

Hypersensitivity

Other preparations

Oxygen should be kept as compressed gas or liquid at cryogenic temperature, in appropriate containers complying with the safety regulations of the national authority. Valves or taps should not be lubricated with oil or grease.