Betamethasone + Neomycin Sulphate (Topical)
Indications
This cream is usually useful for the
treatment of superficial infections caused by gram-positive and
gramnegative microorganisms. It is also useful in burns, regeneration of
new skin in wounds and ulceration, otitis externa, postoperative
infections, neuro-dermatitis and eczema. It may be used as an adjunct to
systemic steroid therapy in special kind of pyoderma.
Pharmacology
Betamethasone is an active topical
corticosteroid, which produces a rapid response in the inflammatory
dermatoses and cures psoriasis types of skin diseases. Neomycin Sulfate
is a topical broad-spectrum bactericidal amino-glycoside effective
against various kinds of gram-positive and gramnegative pathogens such
as Proteus vulgaris, Staphylococcus aureus etc. This preparation has
effective penetration and uniform distribution capacity, so it is very
effective in hairy and intertriginous places. This preparation is very
effective for the treatment of wet ulceration of the skin.
Dosage & Administration
Use in adults: This
preparation should be applied to the affected parts of the skin as a
thin layer for 3 to 4 times daily. In chronic conditions, withdrawal of
treatment is carried out by decreasing the frequency of application
until the cream is applied as infrequently as once a week. Or as
directed by the physician.
Use in children: Do not use it on children under 1 year of age. A course of treatment for a child should not normally last more than 5 days unless otherwise stated by your physician.
Use in children: Do not use it on children under 1 year of age. A course of treatment for a child should not normally last more than 5 days unless otherwise stated by your physician.
Interaction
There are no significant drug interactions reported with Betamethasone Valerate BP and Neomycin Sulphate BP Cream/Ointment.
Contraindications
This preparation is contraindicated to the
patients who are hypersensitive to any of its components. It should not
be used for the treatment of otitis externa when the eardrum is
perforated. It is contraindicated in skin lesions caused by infection
with viruses and fungi.
Side Effects
This preparation is well tolerated. But
prolonged and high doses may cause Cushing's syndrome, acne, thinning
and dilatation of blood vessels, particularly when occlusive dressings
are used.
Pregnancy & Lactation
This preparation should not be used extensively in pregnancy.
Precautions & Warnings
Long term continuous topical therapy of
this preparation should be avoided, which may produce many resistant
micro organisms. So, accurate dose of this preparation should be used in
infected areas only.
Therapeutic Class
Aural steroid & antibiotic combined preparations
Storage Conditions
Keep below 30°C temperature, away from light & moisture. Keep out of the reach of children.
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