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Chlorpheniramine Maleate


Indications

Chlorpheniramine Maleate is indicated in the following indications-
  • Urticaria
  • Sensitivity reactions
  • Angioneurotic edema
  • Vasomotor rhinitis
  • Cough
  • Common cold
  • Motion sickness and
  • Other allergic conditions.


Pharmacology

Chlorpheniramine Maleate is an alkylamine antihistamine. It is one of the most potent histamine H1-receptor blocking agents which is used as a potent antihistamine. This generally causes less sedation than promethazine. Chlorpheniramine Maleate exerts its effects by blocking H1-receptor competitively.



Dosage & Administration

Adult- Usual adult dose is 4 mg every 4-6 hours, maximum 24 mg daily.

Child-
  • 6-12 years: 2 mg every 4-6 hours, maximum 12 mg daily.
  • 2-5 years: 1 mg every 4-6 hours, maximum 6 mg daily.
  • 1-2 years: 1 mg twice daily.
Below 1 year the use of Chlorpheniramine Maleate is not recommended.



Interaction

Chlorphenamine maleate has been reported to be incompatible with calcium chloride, kanamycin sulfate, noradrenaline acid tartrate, pentobarbital sodium, and meglumine adipiodone.


Contraindications

Chlorpheniramine is contraindicated in patients hypersensitive to this agent, in newborn or premature infants.



Side Effects

Chlorpheniramine is well-tolerated, but sometimes drowsiness, dizziness, muscular weakness, and gastrointestinal upset may occur.


Pregnancy & Lactation

This drug should not be used in lactating mother and in pregnancy especially during the first trimester of pregnancy.


Precautions & Warnings

Chlorpheniramine should be used with caution in patients with glaucoma and prostatic hypertrophy. During therapy with chlorpheniramine, caution should be taken in driving vehicles and operating machinery.


Overdose Effects

CNS depression (including sedation, apnea, CV collapse), CNS stimulation (including insomnia, hallucination, tremors, convulsions), tinnitus, blurred vision, dizziness, ataxia, hypotension. Stimulation and atropine-like signs and symptoms (including dry mouth, fixed dilated pupils, flushing, hyperthermia, Gl symptoms) are more likely in children.


Therapeutic Class

Sedating Anti-histamine


Storage Conditions

Store in a cool (Below 25°C temperature) and dry place protected from light. Keep out of the reach of children.


Alerjess Syrup

Alerjess Syrup

IndicationsChlorpheniramine Maleate is indicated in the following indications-UrticariaSensitivity r..

20.00Tk.

Alerjess Tablet 4 mg

Alerjess Tablet 4 mg

IndicationsChlorpheniramine Maleate is indicated in the following indications-UrticariaSensitivity r..

0.20Tk.

Antista Syrup 100 ml bottle

Antista Syrup 100 ml bottle

IndicationsChlorpheniramine Maleate is indicated in the following indications-UrticariaSensitivity r..

21.85Tk.

Biocin Syrup 100 ml bottle

Biocin Syrup 100 ml bottle

IndicationsChlorpheniramine Maleate is indicated in the following indications-UrticariaSensitivity r..

21.78Tk.

Biocin Tablet 4 mg

Biocin Tablet 4 mg

IndicationsChlorpheniramine Maleate is indicated in the following indications-UrticariaSensitivity r..

0.20Tk.

Cloramin Syrup 100 ml bottle

Cloramin Syrup 100 ml bottle

IndicationsChlorpheniramine Maleate is indicated in the following indications-UrticariaSensitivity r..

21.85Tk.

Expilin Syrup 60 ml bottle

Expilin Syrup 60 ml bottle

IndicationsChlorpheniramine Maleate is indicated in the following indications-UrticariaSensitivity r..

11.03Tk.

Expilin Tablet 4 mg

Expilin Tablet 4 mg

IndicationsChlorpheniramine Maleate is indicated in the following indications-UrticariaSensitivity r..

0.20Tk.

Histacin Injection 10 mg/ml

Histacin Injection 10 mg/ml

IndicationsChlorpheniramine Maleate is indicated in the following indications-UrticariaSensitivity r..

3.35Tk.

Histacin Syrup 100 ml bottle

Histacin Syrup 100 ml bottle

IndicationsChlorpheniramine Maleate is indicated in the following indications-UrticariaSensitivity r..

21.85Tk.

Histacin Syrup 60 ml bottle

Histacin Syrup 60 ml bottle

IndicationsChlorpheniramine Maleate is indicated in the following indications-UrticariaSensitivity r..

14.94Tk.

Histacin Tablet 4 mg

Histacin Tablet 4 mg

IndicationsChlorpheniramine Maleate is indicated in the following indications-UrticariaSensitivity r..

0.29Tk.

Histal Syrup 2 mg/5 ml

Histal Syrup 2 mg/5 ml

IndicationsChlorpheniramine Maleate is indicated in the following indications-UrticariaSensitivity r..

14.94Tk.

Histal Tablet 4 mg

Histal Tablet 4 mg

IndicationsChlorpheniramine Maleate is indicated in the following indications-UrticariaSensitivity r..

0.21Tk.

Histalex Syrup 100 ml bottle

Histalex Syrup 100 ml bottle

IndicationsChlorpheniramine Maleate is indicated in the following indications-UrticariaSensitivity r..

21.85Tk.

Histalex Tablet 4mg

Histalex Tablet 4mg

IndicationsChlorpheniramine Maleate is indicated in the following indications-UrticariaSensitivity r..

0.30Tk.

Histin Tablet 4 mg

Histin Tablet 4 mg

IndicationsChlorpheniramine Maleate is indicated in the following indications-UrticariaSensitivity r..

0.21Tk.

Hitagen Syrup 100 ml bottle

Hitagen Syrup 100 ml bottle

IndicationsChlorpheniramine Maleate is indicated in the following indications-UrticariaSensitivity r..

14.00Tk.

Hitagen Syrup 60 ml bottle

Hitagen Syrup 60 ml bottle

IndicationsChlorpheniramine Maleate is indicated in the following indications-UrticariaSensitivity r..

8.00Tk.

Hitagen Tablet 4 mg

Hitagen Tablet 4 mg

IndicationsChlorpheniramine Maleate is indicated in the following indications-UrticariaSensitivity r..

0.20Tk.

Pheramin Syrup 60 ml bottle

Pheramin Syrup 60 ml bottle

IndicationsChlorpheniramine Maleate is indicated in the following indications-UrticariaSensitivity r..

14.90Tk.

Pheramin Tablet 4 mg

Pheramin Tablet 4 mg

IndicationsChlorpheniramine Maleate is indicated in the following indications-UrticariaSensitivity r..

0.20Tk.

Sedilux-M Syrup 2 mg/5 ml

Sedilux-M Syrup 2 mg/5 ml

IndicationsChlorpheniramine Maleate is indicated in the following indications-UrticariaSensitivity r..

21.70Tk.

Sedilux-M Tablet 4 mg

Sedilux-M Tablet 4 mg

IndicationsChlorpheniramine Maleate is indicated in the following indications-UrticariaSensitivity r..

0.20Tk.

Sinamin Syrup 100 ml bottle

Sinamin Syrup 100 ml bottle

IndicationsChlorpheniramine Maleate is indicated in the following indications-UrticariaSensitivity r..

21.85Tk.

Sinamin Tablet 4 mg

Sinamin Tablet 4 mg

IndicationsChlorpheniramine Maleate is indicated in the following indications-UrticariaSensitivity r..

0.30Tk.

Winkol Syrup 100 ml bottle

Winkol Syrup 100 ml bottle

IndicationsChlorpheniramine Maleate is indicated in the following indications-UrticariaSensitivity r..

21.00Tk.

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