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Fexofenadine Hydrochloride

Indications

Fexofenadine Hydrochloride is indicated for the relief of symptoms associated with seasonal allergic rhinitis in adults and children. It is also indicated for the treatment of uncomplicated skin manifestations of chronic idiopathic urticaria.

Pharmacology

Fexofenadine Hydrochloride is an antihistamine with selective peripheral H1-receptor antagonist activity. It is rapidly absorbed after oral administration and peak plasma concentration is reached in 2-3 hours. It does not appear to cross the blood brain barrier.

Dosage & Administration

Seasonal Allergic Rhinitis-

Adults and children 12 years and older:
  • Tablet: 60 mg twice daily or 120 mg once daily or 180 mg once daily
  • In case of impaired renal function: 60 mg once daily
Children from 6 to 11 years:
  • Tablet: 30 mg twice daily or 60 mg once daily
  • In case of impaired renal function: 30 mg once daily
Children from 2 to 11 years
  • Suspension: 30 mg or 5 ml twice daily
  • In case of impaired renal function: 30 mg or 5 ml once daily


Chronic Idiopathic Urticaria-

Adults and children 12 years and older:
  • Tablet: 60 mg twice daily or 120 mg once daily or 180 mg once daily 
  • In case of impaired renal function: 60 mg once daily
Children from 6 to 11 years:
  • Tablet: 30 mg twice daily or 60 mg once daily
  • In case of impaired renal function: 30 mg once daily
Children from 6 months to less than 2 years:
  • Suspension: 15 mg or 2.5 ml (1/2 tsp) twice daily
  • In case of impaired renal function: 15 mg or 2.5 ml (1/2 tsp) once daily
Children from 2 to 11 years:
  • Suspension: 30 mg or 5 ml (1 tsp) twice daily
  • In case of impaired renal function: 30 mg or 5 ml (1 tsp) once daily

Interaction

Plasma concentration of Fexofenadine Hydrochloride have been increased when given with erythromycin or ketoconazole. Aluminium and magnesium hydroxide containing antacid reduces the absorption of Fexofenadine Hydrochloride.

Contraindications

Contraindicated in patients with known hypersensitivity to Fexofenadine Hydrochloride or any of its ingredients.

Side Effects

Common side effects are headache, fatigue, drowsiness, nausea, dry mouth and gastrointestinal disturbances.

Pregnancy & Lactation

US FDA pregnancy category of Fexofenadine Hydrochloride is C. So, Fexofenadine Hydrochloride should be avoided in pregnancy and lactation unless the potential benefits to the other outweigh the possible risks to the fetus.

Precautions & Warnings

Caution should be exercised in elderly patient and patient with decreased renal function.

Overdose Effects

In case of an overdose, standard measures to remove any unabsorbed drug should be employed. Symptomatic and supportive treatment is recommended. There has been no reported case of an acute overdose of Fexofenadine hydrochloride.

Therapeutic Class

Non-sedating antihistamines

Storage Conditions

Keep in a dry place away from light and heat. Keep out of the reach of children.
Fenofex Oral Suspension 50 ml bottle

Fenofex Oral Suspension 50 ml bottle

IndicationsFexofenadine Hydrochloride is indicated for the relief of symptoms associated with season..

48.00Tk.

Fenofex Tablet 120 mg

Fenofex Tablet 120 mg

IndicationsFexofenadine Hydrochloride is indicated for the relief of symptoms associated with season..

8.00Tk.

Fenofex Tablet 180 mg

Fenofex Tablet 180 mg

IndicationsFexofenadine Hydrochloride is indicated for the relief of symptoms associated with season..

9.00Tk.

Fenofex Tablet 60 mg

Fenofex Tablet 60 mg

IndicationsFexofenadine Hydrochloride is indicated for the relief of symptoms associated with season..

3.50Tk.

Fenox Tablet 120 mg

Fenox Tablet 120 mg

IndicationsFexofenadine Hydrochloride is indicated for the relief of symptoms associated with season..

7.00Tk.

Fexo Oral Suspension 50 ml bottle

Fexo Oral Suspension 50 ml bottle

IndicationsFexofenadine Hydrochloride is indicated for the relief of symptoms associated with season..

48.33Tk.

Fexo Tablet 120 mg

Fexo Tablet 120 mg

IndicationsFexofenadine Hydrochloride is indicated for the relief of symptoms associated with season..

8.00Tk.

Fexo Tablet 180 mg

Fexo Tablet 180 mg

IndicationsFexofenadine Hydrochloride is indicated for the relief of symptoms associated with season..

10.00Tk.

Fexo Tablet 60 mg

Fexo Tablet 60 mg

IndicationsFexofenadine Hydrochloride is indicated for the relief of symptoms associated with season..

3.52Tk.

Fexodin Oral Suspension 50 ml bottle

Fexodin Oral Suspension 50 ml bottle

IndicationsFexofenadine Hydrochloride is indicated for the relief of symptoms associated with season..

50.00Tk.

Fexodin Tablet 120 mg

Fexodin Tablet 120 mg

IndicationsFexofenadine Hydrochloride is indicated for the relief of symptoms associated with season..

8.00Tk.

Fexofast Oral Suspension 50 ml bottle

Fexofast Oral Suspension 50 ml bottle

IndicationsFexofenadine Hydrochloride is indicated for the relief of symptoms associated with season..

50.00Tk.

Fexofast Tablet 120 mg

Fexofast Tablet 120 mg

IndicationsFexofenadine Hydrochloride is indicated for the relief of symptoms associated with season..

8.00Tk.

Fexofast Tablet 180 mg

Fexofast Tablet 180 mg

IndicationsFexofenadine Hydrochloride is indicated for the relief of symptoms associated with season..

9.00Tk.

Fexofast Tablet 60 mg

Fexofast Tablet 60 mg

IndicationsFexofenadine Hydrochloride is indicated for the relief of symptoms associated with season..

3.50Tk.

Fexomin Oral Suspension 50 ml bottle

Fexomin Oral Suspension 50 ml bottle

IndicationsFexofenadine Hydrochloride is indicated for the relief of symptoms associated with season..

48.00Tk.

Fexomin Tablet 120 mg

Fexomin Tablet 120 mg

IndicationsFexofenadine Hydrochloride is indicated for the relief of symptoms associated with season..

7.00Tk.

Fexomin Tablet 180 mg

Fexomin Tablet 180 mg

IndicationsFexofenadine Hydrochloride is indicated for the relief of symptoms associated with season..

9.00Tk.

Fexomin Tablet 60 mg

Fexomin Tablet 60 mg

IndicationsFexofenadine Hydrochloride is indicated for the relief of symptoms associated with season..

5.00Tk.

Fexona Oral Suspension 50 ml bottle

Fexona Oral Suspension 50 ml bottle

IndicationsFexofenadine Hydrochloride is indicated for the relief of symptoms associated with season..

48.00Tk.

Fexona Tablet 120 mg

Fexona Tablet 120 mg

IndicationsFexofenadine Hydrochloride is indicated for the relief of symptoms associated with season..

6.50Tk.

Fexona Tablet 180 mg

Fexona Tablet 180 mg

IndicationsFexofenadine Hydrochloride is indicated for the relief of symptoms associated with season..

8.00Tk.

Fexoral Oral Suspension 50 ml bottle

Fexoral Oral Suspension 50 ml bottle

IndicationsFexofenadine Hydrochloride is indicated for the relief of symptoms associated with season..

48.00Tk.

Fexoral Tablet 120 mg

Fexoral Tablet 120 mg

IndicationsFexofenadine Hydrochloride is indicated for the relief of symptoms associated with season..

90.00Tk.

Fexoral Tablet 180 mg

Fexoral Tablet 180 mg

IndicationsFexofenadine Hydrochloride is indicated for the relief of symptoms associated with season..

10.00Tk.

Fixal Oral Suspension 50 ml bottle

Fixal Oral Suspension 50 ml bottle

IndicationsFexofenadine Hydrochloride is indicated for the relief of symptoms associated with season..

48.33Tk.

Fixal Tablet 120 mg

Fixal Tablet 120 mg

IndicationsFexofenadine Hydrochloride is indicated for the relief of symptoms associated with season..

8.00Tk.

Fixal Tablet 180 mg

Fixal Tablet 180 mg

IndicationsFexofenadine Hydrochloride is indicated for the relief of symptoms associated with season..

10.00Tk.

Fixal Tablet 30 mg

Fixal Tablet 30 mg

IndicationsFexofenadine Hydrochloride is indicated for the relief of symptoms associated with season..

3.51Tk.

Fixal Tablet 60 mg

Fixal Tablet 60 mg

IndicationsFexofenadine Hydrochloride is indicated for the relief of symptoms associated with season..

5.02Tk.

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