Caridol Tablet 250 mg

Carisoprodol is indicated for-

• The relief of discomfort associated with acute, painful musculoskeletal conditions in adults.
• Sedation and decrease anxiety in patients with severe pain.
• Used as an adjunct in physical therapy in injuries.

Carisoprodol is a GABA-A receptor indirect agonist with CNS chloride channel conductance effect. GABA receptor agonists typically produce sedative effect and may also cause other effects such as anxiolytic, anticonvulsant and muscle relaxant. Metabolite of Carisoprodol, Meprobamate, has anxiolytic and sedative properties. Carisoprodol decreases the impulses from brain and spinal cord to the muscle. This causes the muscle to relax and hence decrease the spasm. It has no direct action on muscle itself.

Adults (18 years and older): The recommended dose of Carisoprodol is 250 mg three times daily and at bedtime (4 times daily). The recommended maximum duration of Carisoprodol use is up to two or three weeks. Caution should be taken in patients with renal and hepatic impairment and also with reduced CYP2C19 activity.

Carisoprodol is contraindicated in patients with a history of acute intermittent porphyria or a hypersensitivity reaction to a carbamate such as meprobamate.

Common side effects are drowsiness, dizziness and headache.