Veserc 16 Tablet
- Brand:Unimed Unihealth Pharmaceuticals Ltd.
- Product Code: Betahistine Dihydrochloride 16mg
- Availability: In Stock
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4.75Tk.
Indications of Veserc 16 Tablet
Meniere's illness and Meniere-like syndromes are characterized by vertigo, tinnitus, and/or progressive hearing loss, sometimes accompanied by nausea and vomiting.
Pharmacology of Veserc 16 Tablet
Betahistine has a multifaceted method of action. Meniere's illness is thought to be caused by a breakdown in the ear's endolymphatic fluid equilibrium. Betahistine is primarily an agonist for the histamine H1 receptor. The stimulation of H1-receptors in the inner ear generates a vasodilatory effect in the blood vessels, resulting in enhanced permeability and a reduction in endolymphatic pressure; this action prevents the rupture of the labyrinth, which can contribute to Ménière's disease hearing loss. Betahistine is also thought to relieve symptoms of vertigo by minimizing asymmetrical functioning of sensory vestibular organs and boosting vestibulocochlear blood flow.
In addition to the aforementioned processes, betahistine functions as a histamine H3-receptor antagonist, increasing histamine turnover from postsynaptic histaminergic nerve receptors and, as a result, enhancing H1-agonist activity. H3-receptor antagonism raises levels of neurotransmitters in the brainstem, particularly serotonin, which inhibits vestibular nuclei activity, restoring normal balance and reducing vertigo symptoms.
Dosage & Administration of Veserc 16 Tablet
The usual initial dose: 8 mg to 16 mg three times daily taken preferably with meals.
Maintenance dose: Up to 48 mg daily has been recommended. Betahistine is not recommended for use in children.
Interaction of Veserc 16 Tablet
There have been no documented occurrences of dangerous interactions. Although a potential antagonism between Betahistine and antihistamines should be expected, no such interactions have been documented.
Contraindications
In pheochromocytoma, betahistine is not recommended.
Side Effects of Veserc 16 Tablet
Betahistine is generally well tolerated, and no major side effects have been reported. Gastrointestinal problems, headaches, rashes, and pruritus have all been reported in rare cases.
Pregnancy & Lactation
In Pregnancy: Although there is no known teratogenic impact in animals, the safety of Betahistine in human pregnancy has not been fully proven. Before administering Betahistine during pregnancy, it's important to weigh the potential advantages carefully.
Betahistine is excreted in similar amounts in the breast milk of nursing mothers as it is in the plasma. The neonate's toxicity at these amounts is unknown.
Precautions & Warnings
Patients with bronchial asthma and peptic ulcer disease should be cautious.
Therapeutic Class
Meniere's disease medications
Storage Conditions
Keep the temperature below 30°C and away from light and moisture. Keep out of children's reach.
Pharmaceutical Name of Veserc 16 Tablet
UniMed UniHealth Pharmaceuticals Ltd
Generic of Veserc 16 Tablet
Tags: Veserc 16 Tablet