Otosporin 5 Ear Drop

Generic

Hydrocortisone + Neomycin Sulphate + Polymixin B

Indications

Ear drops containing hydrocortisone, Neomycin Sulphate, and Polymixin B are recommended for the treatment of bacterial ear infections. It is ineffective for other forms of ear infections. Any antibiotic's efficacy might be reduced if it is used unnecessarily or excessively.

Pharmacology

Antibiotics are a class of drugs that include polymyxin B sulphate and neomycin sulphate. They eliminate the bacteria that cause ear infections. The combination's anti-infective components are incorporated to offer action against certain organisms sensitive to them. Staphylococcus aureus, Escherichia coli, Haemophilus influenzae, Klebsiella-Enterobacter species, Neisseria species, and Pseudomonas aeruginosa are all resistant to neomycin sulfate and polymyxin B sulfate. This medication is ineffective against Serratia marcescens and streptococci, including Streptococcus pneumoniae.

Hydrocortisone is a kind of medication known as a steroid. It aids in the reduction of swelling and discomfort produced by the illness. Hydrocortisone suppresses the inflammatory response to a number of substances and may cause healing to be delayed. Because hydrocortisone may reduce the body's defensive system against infection, a concurrent antimicrobial medication may be administered if this suppression is deemed clinically relevant in a specific situation.

Dosage

Adults and children over 3 years old: Apply 3 drops into the affected ear up to four times a day, for up to 7 days. Make sure you finish the course of this drop which your doctor has prescribed.

Administration

• Shake the closed bottle gently before each use
• Clean and dry the ears
• Do not use soap, it may stop the medicine working
• Do not put the drops in your eyes.

Interaction

Toxicity when used with neurotoxic, ototoxic, or nephrotoxic medicines. If substantial quantities of neomycin are ingested, neuromuscular blocking drugs may cause increased neuromuscular blockade and perhaps respiratory depression.

Contraindications

Contraindicated-

• if you are allergic (hypersensitive) to polymyxin B sulphate, neomycin sulphate, hydrocortisone or any of the other ingredients of this preparation.
• if you are allergic (hypersensitive) to aminoglycoside antibiotics such as framycetin, kanamycin or gentamicin
• if you have a perforated ear drum
• if you have either a viral, fungal or tubercular (TB) infection
• for a child under 3 years old.

Side Effects

The following adverse effects are uncommon with this medication: symptoms appear to worsen rather than improve, skin becomes red, scaly, and itching.

Pregnancy & Lactation

If you are pregnant or want to become pregnant, do not take this preparation. Do not use this if you are breastfeeding.

Precautions & Warnings

If you have renal issues, proceed with caution. If you have a long-standing outer ear infection.

Therapeutic Class

Preparations including an ophthalmic steroid and an antibiotic, as well as Ophthalmic Steroid preparations

Storage Conditions

Keep out of children's reach and sight. Store at temperatures no higher than 25°C. To protect it from light, it should be stored in a box.

Pharmaceutical Name

Glaxo Smithkline Bangladesh Limited