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Osmolax 200 ml


  • Product Code: Lactulose 3.35/5%
  • Availability: In Stock

  • 237.50Tk.



Generic

Lactulose

 

Indications

Constipation (Chronic Constipation): The initial treatment for chronic constipation should include a high-fiber diet (vegetables, salads, fruits, etc. ), plenty of liquids, and plenty of physical activity. Lactulose should only be used if these measures are ineffective.

 

Pharmacology

Lactulose is a disaccharide that has been synthesized. Lactulose is metabolized in the colon by saccharolytic bacteria, which produces low molecular weight organic acids (primarily lactic acid), which lowers the pH of the colon contents, promotes water retention via an osmotic effect, and thus increases peristaltic activity.

 

Dosage & Administration

In constipation ( chronic constipation):

  • Adults: Initially 3-6 tea-spoons daily, In long-term therapy 1½-6 tea-spoons daily
  • Children up to 14 years: Initially 3 tea-spoons daily, In long-term therapy 1-2 tea-spoons daily
  • Infants and toddlers: Initially 1-2 tea-spoons daily, In long-term therapy 1 tea-spoon daily

In damaged intestinal flora:

  • Adults: 1-2 tea-spoons daily
  • Children: 1 tea-spoon daily

For reduction of blood ammonia level:

  • Hyper-ammoniemia in hepatopathy: a maximum of 18-30 tea-spoons daily.
  • In portal systemic encephalopathy: hourly doses of 6-9 tea-spoons of Lactulose solution may be used to induce the rapid laxation. When the laxative effect has been achieved, the dose may then be reduced.

 

Interaction

With lactulose, there are no significant drug interactions. In abuse, potassium deficiency can amplify the glycosidic effect of cardiac glycosides.

 

Contraindications

Galactose and/or lactose hypersensitivity; galactose-free diet; gastro-cardial symptom complex; suspected intestinal obstruction

 

Side Effect

Flatulence, cramps, and abdominal discomfort may occur at the start of treatment; this is quickly resolved by lowering the dose. Overdosing can cause diarrhoea. Electrolyte loss is a common side effect of drug abuse (primarily potassium).

 

Pregnancy & Lactation

Lactulose is classified as a pregnancy category B by the US Food and Drug Administration. Lactulose has been shown in studies to have no negative effects. A registered physician must make decisions about use during pregnancy and lactation.

 

Precautions & Warnings

Patients who are intolerant to lactulose should be given the sugar with caution. The dose used in the treatment of (pre) coma hepaticum is usually much higher, and diabetics should be aware of this.

 

Therapeutic Class

Purgatives based on osmotic pressure

 

Storage Conditions

Keep away from light and heat in a dry place. Keep out of children's reach.

 

Pharmaceutical Name

Square Pharmaceuticals Ltd.

Tags: Osmolax 200 ml