Yamadin-20 Tablet

Famotidine is used to treat a variety of conditions-

• Ulcer in the stomach
• Ulcer in the duodenum
• Ulcer anastomotic
• Acute stress ulcer is a type of ulcer that appears suddenly.
• Reflux esophagitis (reflux esophagitis) is a condition in which the
• The Zollinger-Ellison syndrome is a condition that affects people.

Famotidine is also used to treat acute gastritis and chronic gastritis that has reached an acute exacerbation stage.

Pharmaceutical Name

Pharmacology

Famotidine works by blocking histamine H2-receptors. Famotidine completely blocks histamine's action on parietal cell H2-receptors. It suppresses gastric acid secretion in the basal, overnight, and pentagastrin-stimulated states. Famotidine's H2- receptor antagonist activity is reversible because the drug dissociates slowly from the H2-receptor.

Dosage & Administration

Tablet:

• For gastric ulcer, duodenal ulcer, anastomotic ulcer, upper gastro-intestinal hemorrhage, reflux esophagitis and Zollinger-Ellison syndrome: Usual dose for adults: Famotidine 20 mg twice daily (after breakfast and after supper or before bed time) or Famotidine 40 mg can be administered orally once daily at bed time.
• For the treatment of acute gastritis, chronic gastritis in acute exacerbation stage: Usual dosage for adults is Famotidine 20 mg orally twice a day (after breakfast and after supper or before bed time). Also Famotidine 40 mg can be orally administered once a day (before bed time), dosage should be adjusted according to age and symptoms. Most ulcer patients heal within 4-8 weeks. For maintenance therapy the recommended oral dose is 20 mg once daily. Or, as directed by the registered physician.

Powder for Suspension:
Gastroesophageal Reflux Disease(GERD):

• <1 year of age: 0.5 mg/kg/dose of famotidine oral suspension up to 8 weeks once daily in patients
• Age 3 to 11 months: 0.5 mg/kg/dose twice daily up to 8 weeks
• Age 1 to 2 months: 0.5 mg/kg/dose once daily up to 8 weeks
• Neonates: 0.5 mg/kg/dose maximum once daily up to 8 weeks

Patients 1-16 years of age:

• Gastroesophageal Reflux Disease(GERD): 1 mg/kg/day p.o. divided b.i.d. up to 40 mg b.i.d.
• Duodonal ulcer: 0.5 mg/kg/day p.o. at bedtime or divided b.i.d. up to 40 mg/day.
• Peptic ulcer: 0.5 mg/kg/day p.o. at bedtime or divided b.i.d. up to 40 mg/day.
• Maintenance therapy: 40 mg at daily night.
• Reflux esophagitis: 2 mg/kg/day
• Zollinger-Ellison Syndrome: 40 mg 3 times daily.

Interaction of Yamadin-20

Hypersensitivity to any of the drug's components.

Contraindications

Hypersensitivity to any of the drug's components.

Side Effects of Yamadin-20

Constipation, diarrhoea, dry mouth, nausea, vomiting, tachycardia, high blood pressure, headache, drowsiness, or insomnia are all rare side effects.

Pregnancy & Lactation

Category B pregnancy. In pregnant women, there are no adequate and well-controlled studies. This medication should only be used during pregnancy if absolutely necessary. When Famotid is given to a nursing woman, it should be done with caution.

Precautions & Warnings

Depending on the severity of the disease, the drug should be used in the smallest amount possible. Patients who are elderly, have renal failure, or have hepatic disorders should be given the drug with caution.

Therapeutic Class

Antagonist of the H2 receptor

Storage Conditions

Keep the temperature below 30°C and away from light and moisture. Keep out of children's reach.