Locid 400 Tablet

Indications of Locid 400

• Heartburn
• Indigestion
• Gastric Hyperacidity
• Peptic ulcer disease

Dosage & Administration of Locid 400

Oral
Antacid

Adult: Up to 1 g daily.
Oral
Hyperphosphataemia in patients with chronic renal failure
Adult: Dose is adjusted to the individual patient's requirement. Up to 10 g/day may be given in divided doses with meals.
Max Dosage: 10 g daily in divided doses.

Locid 400 may be taken with or without food.

Interaction

Enhanced absorption with citrates or ascorbic acid. Decreases absorption of allopurinol, tetracyclines, quinolones, cephalosporins, biphosphonate derivatives, corticosteroids, cyclosporin, delavirdine, Fe salts, imidazole antifungals, isoniazid, mycophenolate, penicillamine, phosphate supplements, phenytoin, phenothiazines, trientine.

Contraindications

Hypersensitivity to aluminium salts.

Side Effects

Constipation; intestinal obstruction (with large doses); phosphate depletion may occur with prolonged admin or large doses.

Pregnancy & Lactation

Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of Locid 400 in pregnant women despite potential risks

Precautions & Warnings

Chronic renal impairment; CHF; oedema; cirrhosis and low Na diets; patients with recent GI haemorrhage. Administer 2-3 hrs before/after another medication to minimise drug interactions, Pregnancy and lactation.

Storage Conditions

Keep out of the reach of children.

Pharmaceutical Name

ACI Limited

Generic of Locid 400

Aluminium Hydroxide