Fungistin 12 ml Suspension
- Brand:Beximco Pharmaceuticals Limited
- Product Code: Nystatin 100000%
- Availability: In Stock
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21.67Tk.
Indications
Nystatin is an antifungal antibiotic that works against Candida albicans and other yeasts and yeast-like fungi. It's used to prevent and cure Candida infections of the mouth, esophagus, and gastrointestinal tract. It effectively prevents oral candidiasis in children born to moms who have vaginal candidiasis. It's used to prevent Candida overgrowth during broad-spectrum antibiotic treatment.
Pharmacology
Nystatin inhibits the growth of a wide range of pathogenic and nonpathogenic yeasts and fungi, including Candida albicans. Nystatin works against fungi by binding to sterols in the cell membrane of the fungus. The membrane loses its ability to operate as a selective barrier as a result of binding, and potassium and other cellular contents are lost. It has a low absorption rate in the gastrointestinal tract.
Administration & Dosage
Children:
- In intestinal and oral candidiasis (thrush): 1,00,000 units (1 ml) should be dropped into the mouth four times daily.The longer the suspension is kept in contact with the affected area in the mouth, before swallowing, the greater will be its effect.
- For prophylaxis in the newborn: The suggested dose is 1,00,000 units (1 ml) once daily or as prescribed by the physician.
Adult:
- For the treatment of intestinal or esophageal candidiasis: 5,00,000 units (5 ml) by mouth 3 or 4 times daily. The dose may be doubled, if required.
- For prophylaxis of intestinal candidiasis in adults: 10,00,000 units (10 ml) daily.
- For prophylaxis to suppress the over growth of Candida albicans in patients receiving broad spectrum antibiotic therapy: 10,00,000 units (10 ml) daily.
- For the treatment of dental sores and oral infection: 1,00,000 units (1 ml) suspension should be dropped into the mouth four times daily.
Elderly: Older people with intestinal candidiasis who are unable to swallow tablets should be given 5,00,000 units (5 ml) suspension four times daily.
Contraindications
There are no known contraindication to the use of Nystatin except hypersensitivity to the drug.
Side Effects
Nausea, vomiting and diarrhoea have occasionally been reported with doses of Nystatin exceeding 4 to 5 million units daily. No systemic effects or allergic reactions have been associated with its oral use.
Pregnancy & Lactation
Pregnancy category C: Mouth/Throat/PO/Topical
Pregnancy category A: Vaginal
Precautions & Warnings
Because absorption from the gastrointestinal tract is minimal, no extra precautions are required during pregnancy or lactation.
Therapeutic Class
Drugs for subcutaneous and mycoses, Drugs used in Vaginal and Vulval condition.
Storage Conditions
Protect from light and moisture by storing below 30°C. Keep the medicine out of children's reach.