Fungi MH 10 Cream

Indications

For the topical treatment of inflamed dermatoses, such as intertrigo and infected eczema, where infection by susceptible organisms and inflammation coexist. Eczema or dermatitis, including atopic eczema, primary irritant or contact allergic eczema, or seborrheic eczema, including acne-related eczema Interiginous eczema, including inflammatory interigo, perianal, and genital dermatitis, is also treated with this medication. Dermatophytes and pathogenic yeasts (e.g. Candida spp.) are vulnerable to miconazole, as are numerous Gram-positive bacteria, including several strains of Streptococcus and Staphylococcus.

Pharmacology

Miconazole is a substituted imidazole, one of the azoles, and can be used to treat candidiasis and superficial dermatophytosis, tinea versicolor, Acanthamoeba, seborrheic dermatitis, and other skin infections. It is also active against Aspergillus, Cryptococcus neoformans, Pseudomonas borderi, and some Gram positive bacteria (such as Staphylococcus and Streptococcus).

Hydrocortisone is a naturally occurring glucocorticoid that is now prepared synthetically. Its important role is in skin damage such as inflammation. It also has antipruritic, antifungal, and vasoconstrictor activities.

Miconazole is an imidazole antifungal agent that can interfere with ergosterol synthesis, thereby changing the permeability of the cell membrane of sensitive fungi. This leads to the death of fungi, and when applied to the skin, hydrocortisone is absorbed into skin cells. It can prevent the release of certain chemicals that can cause inflammation. Therefore, hydrocortisone reduces inflammation.

Dosage & Administration

Apply to the affected area as a thin film two or four times daily for 1 to 2 weeks. Rub it well with your finger until this cream fully vanished on the skin. Treatment should be continued at least one week after the disappearance of all signs and symptoms. The same dosage applies to both adults and children.

Interaction

Amphotericin antagonizes the activity of Miconazole.

Contraindications

Individuals who are hypersensitive to it or any of its components should avoid it. Without the advice of a physician, it should not be taken in pregnant or lactating mothers.

Side Effects

Local sensitivity is a rare occurrence. Long-term use may cause the adrenal gland to produce fewer natural hormones.

Pregnancy & Lactation

Corticosteroids given to pregnant animals in excessive quantities can induce embryonic development problems. During pregnancy, topical steroids should be used sparingly.

Precautions & Warnings

Only on a licensed physician's prescription can it be dispensed. Keep out of children's reach. In the case of long-term use in youngsters and the elderly, exercise caution or seek medical advice.

Therapeutic Class

Hydrocortisone & Combined preparations

Storage Conditions

Keep below 30°C temperature, away from light & moisture. Keep out of the reach of children.

Pharmaceutical Name

Edruc Ltd.