Nysol 12 ml Oral Suspension

Indications

Nystatin is an antifungal antibiotic that can fight a variety of yeast and yeast-like fungi, including Candida albicans. It is used to prevent and treat oral, esophagus and intestinal candida infections. Provide effective oral yeast infection prevention for babies born to mothers suffering from vaginal yeast infections. It is used to prevent Candida overgrowth during treatment with broad-spectrum antibiotics.

Pharmacology

Nystatin inhibits the growth of a wide range of pathogenic and nonpathogenic yeasts and fungi, including Candida albicans. Nystatin works against fungi by binding to sterols in the cell membrane of the fungus. The membrane loses its ability to operate as a selective barrier as a result of binding, and potassium and other cellular contents are lost. It's not well absorbed.

Dosage & Administration

Children:

In intestinal and oral candidiasis (thrush): 1,00,000 units (1 ml) should be dropped into the mouth four times daily.The longer the suspension is kept in contact with the affected area in the mouth, before swallowing, the greater will be its effect.

For prophylaxis in the newborn: The suggested dose is 1,00,000 units (1 ml) once daily or as prescribed by the physician.

Adult:

For the treatment of intestinal or esophageal candidiasis: 5,00,000 units (5 ml) by mouth 3 or 4 times daily. The dose may be doubled, if required.For prophylaxis of intestinal candidiasis in adults: 10,00,000 units (10 ml) daily.

For prophylaxis to suppress the over growth of Candida albicans in patients receiving broad spectrum antibiotic therapy: 10,00,000 units (10 ml) daily.

For the treatment of dental sores and oral infection: 1,00,000 units (1 ml) suspension should be dropped into the mouth four times daily.

Elderly: Older people with intestinal candidiasis who are unable to swallow tablets should be given 5,00,000 units (5 ml) suspension four times daily.

Interaction

There have been no drug interaction studies with the Nystatin, although there have been studies with the individual components.

Side Effects

Nausea, vomiting and diarrhoea have occasionally been reported with high doses of Nystatin. No systemic effects or allergic reactions have been associated with its oral dose.

Pregnancy & Lactation

Mouth/Throat/PO/Topical: Pregnancy catagory C
Vaginal: Pregnancy catagory A

Precautions & Warnings

Because absorption from the gastrointestinal tract is minimal, no extra precautions are required during pregnancy or lactation.

Therapeutic Class

Drugs for subcutaneous and mycoses, Drugs used in Vaginal and Vulval condition.

Storage Conditions

Protect from light and store in a cool, dry location. Keep out of children's reach.

Pharmaceutical Name

Edruc Ltd.