Facebook
Twitter
LinkedIn
Instagram
Tumblr

Nystat 12 ml Oral Suspension


  • 32.50Tk.



Indications

Nystatin is an antifungal antibiotic that may be used to treat a variety of yeasts and yeast-like fungi, including Candida albicans. It is used to prevent and cure Candida infections of the oral cavity, esophagus, and gastrointestinal system. It effectively prevents oral candidiasis in children delivered to moms with vaginal candidiasis. It is used to prevent Candida overgrowth during broad-spectrum antibiotic regimens.

 

Pharmacology

Nystatin has fungicidal or fungistatic action against a wide range of pathogenic and nonpathogenic yeasts and fungi, including Candida albicans. Nystatin's antifungal action is mediated via binding to sterols in the fungal cell membrane. The membrane is no longer able to serve as a selective barrier as a result of binding, and potassium and other cellular components are lost. The gastric system absorbs it weakly.

 

Dosage & Administration

Children:

  • In intestinal and oral candidiasis (thrush): 1,00,000 units (1 ml) should be dropped into the mouth four times daily.The longer the suspension is kept in contact with the affected area in the mouth, before swallowing, the greater will be its effect.
  • For prophylaxis in the newborn: The suggested dose is 1,00,000 units (1 ml) once daily or as prescribed by the physician.

Adult:

  • For the treatment of intestinal or esophageal candidiasis: 5,00,000 units (5 ml) by mouth 3 or 4 times daily. The dose may be doubled, if required.
  • For prophylaxis of intestinal candidiasis in adults: 10,00,000 units (10 ml) daily.
  • For prophylaxis to suppress the over growth of Candida albicans in patients receiving broad spectrum antibiotic therapy: 10,00,000 units (10 ml) daily.
  • For the treatment of dental sores and oral infection: 1,00,000 units (1 ml) suspension should be dropped into the mouth four times daily.

Elderly: Older people with intestinal candidiasis who are unable to swallow tablets should be given 5,00,000 units (5 ml) suspension four times daily.

 

Side Effects

High dosages of Nystatin have occasionally been associated with nausea, vomiting, and diarrhoea. Its oral dosage has not been linked to any systemic effects or allergic reactions.

 

Pregnancy & Lactation

Pregnancy Category C: Mouth/Throat/PO/Topical

Pregnancy Category A: Vaginal

 

Precautions & Warnings

Because absorption from the gastrointestinal system is minimal, no additional precautions are necessary during pregnancy and breastfeeding.

 

Therapeutic Class

Drugs for subcutaneous and mycoses, Drugs used in Vaginal and Vulval condition

 

Storage Conditions

Keep cool and dry, and keep away from direct sunlight. Keep out of children's reach.

 

Pharmaceutical Name

ACME Laboratories Ltd.
 

Tags: Nystat 12 ml Oral Suspension