Neorice Oral Powder 250 ml sachet
- Brand:Eskayef Pharmaceuticals Ltd
- Product Code: Oral Rehydration Salt [Rice Based]
- Availability: In Stock
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12.00Tk.
Composition
500 ml saline: Each sachet contains:
- Sodium Chloride BP 1.3 gm
- Potassium Chloride BP 0.75 gm
- Trisodium Citrate Dihydrate BP 1.45 gm
- Processed Rice Powder Pharma Grade 25 gm
- Sodium Chloride BP 0.65 gm
- Potassium Chloride BP 0.375 gm
- Trisodium Citrate Dihydrate BP 0.725 gm
- Processed Rice Powder Pharma Grade 12.5 gm
Indications
This saline is indicated in-
- Acute fluid and electrolyte loss conditions such as cholera, acute diarrhea & vomiting
- Dehydration
- Severely low concentrations of salts in the blood (severe electrolyte depletion)
Pharmacology
This saline contains essential electrolytes & carbohydrate (in the form of processed rice) which are vital for a dehydrating patient in conditions such as cholera, acute diarrhoea, vomiting & excessive sweating.
In the normal healthy intestine, there is a continuous exchange of water through the intestinal wall- up to 20 liters of water is secreted and very nearly as much is reabsorbed every 24 hours- this mechanism allows the absorption of soluble metabolites from digested food into the bloodstream.
In a state of diarrheal disease, the balance is upset and much more water is secreted than is reabsorbed causing a net loss to the body which can be as high as several liters a day. In addition to water, Chloride ion (CI-), extracellular sodium ion (Na+) & intracellular potassium ion (K+) are also lost. This saline is effectively replenishes the lost electrolytes in the body.
The pharmacokinetics and therapeutic values of the substances of this saline are as follows:
In the normal healthy intestine, there is a continuous exchange of water through the intestinal wall- up to 20 liters of water is secreted and very nearly as much is reabsorbed every 24 hours- this mechanism allows the absorption of soluble metabolites from digested food into the bloodstream.
In a state of diarrheal disease, the balance is upset and much more water is secreted than is reabsorbed causing a net loss to the body which can be as high as several liters a day. In addition to water, Chloride ion (CI-), extracellular sodium ion (Na+) & intracellular potassium ion (K+) are also lost. This saline is effectively replenishes the lost electrolytes in the body.
The pharmacokinetics and therapeutic values of the substances of this saline are as follows:
- Glucose (comes from rice) facilitates the absorption of sodium (and hence water) on a 1:1 molar basis in the small intestine
- Sodium and potassium are needed to replace the body losses of these essential ions during diarrhoea and vomiting
- Citrate corrects the acidosis that occurs as a result of diarrhoea and dehydration
Dosage
The dose depends on the severity of the dehydrating conditions of the patients. Recommended dose after each watery stool are as follows:
- 6 months to 2 years: 50 ml to 100 ml (10 to 20 Teaspoonfuls)
- 2 years to 9 years: 100 ml to 200 ml (20 to 40 teaspoonfuls)
- 10 years and above: 250 ml to 500 ml (1 to 2 glassfuls)
Administration
- Discard any unused reconstituted saline after 5 hours of preparation
- After preparing the saline further heating or boiling is not necessary
- Feeding-bottle should not be used
- Mix the solution with a clean spoon each time before administration
- Syringe without needle may be used to put a small amount of saline into babies' mouth
Interaction
There is no known drug interaction reported.
Contraindications
- Kidney failure resulting in diminished production of urine (oliguria)
- Kidney failure, preventing the production of urine (anuria)
- Obstruction of the stomach or intestines
- Reduced blood flow to vital internal organs (shock)
- Severe and continuous vomiting (intractable vomiting)
- Severe dehydration
- Severe diarrhea in infants.