Clinface
- Brand:Square Pharmaceuticals Ltd.
- Product Code: Clinface 1.2%+0.025%
- Availability: In Stock
-
152.00Tk.
Indications
Clindamycin and
Tretinoin gel is indicated for the topical treatment of Acne vulgaris.
Pharmacology
This is a combination
of lincosamide antibiotic Clindamycin phosphate and retinoid Tretinoin.
Clindamycin binds with the 50s ribosomal subunit of susceptible bacteria and
prevents elongation of peptide chain by interfering with the peptidyl transfer,
thereby suppressing bacterial protein synthesis. Clindamycin inhibits the
activity of Propionibacterium acne as reduces the occurrence of acne. Tretinoin
decreases the cohesiveness of follicular epithelial cells and increases the
turn over thereby brings the comedones out.
Dosage & Administration
Before sleep: Wash the face gently with a mild soap and
water, then pat the skin dry. Apply the Gel with finger tips through the face
gently.
In the morning: Apply a sunscreen after the application of
Gel. Do not wash your face more than 2 or 3 times a day. Apply the sunscreen
cream as needed.
Safety and effectiveness in children below 12 years of age have not been
established.
* চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন'
Interaction
- Concomitant use of other
potentially irritating topical products (medicated or abrasive soaps and
cleansers, soaps and cosmetics that have a strong drying effect, products
with high concentrations of alcohol, astringents, spices or lime) should
be approached with caution.
- While using concomitantly with
Erythromycin, the activity of both Clindamycin and Erythromycin are
decreased. So, Clindamycin should not be used with Erythromycin
concomitantly.
- While using concomitantly with
neuromuscular medicine, the activity of the neuromuscular medicine is
increased. So, care should be taken during these concomitant uses.
Contraindications
Clindamycin and
Tretinoin should not be administered to individuals who are hypersensitive to
Clindamycin or Tretinoin or any other component of the Gel.
Side Effects
Erythema, scaling,
nasopharyngitis, dry skin, cough, sinusitis and diarrhea are the common side
effects.
Pregnancy & Lactation
It is not known
whether Clindamycin or Tretinoin is excreted in human milk. Exercise special
caution while applying Clindamycin or Tretinoin to a nursing mother.
Precautions & Warnings
Clindamycin and
Tretinoin should not be applied to eyes, nose, ear, lips, cut, burn and other
infections. After the application of the Gel, keep away from sunlight.
Therapeutic Class
Topical antibiotic
& retinoid preparations
Storage Conditions
Keep below 25°C
temperature, away from light & moisture. Keep out of the reach of children.
Tags: Clinface