Afrin 0.025%-10 ml

Indications

Nasal congestion caused by acute or chronic rhinitis, the common cold, sinusitis, upper respiratory allergies, epistaxis, and hay fever is treated with Oxymetazoline Hydrochlorid. It's also used to treat otitis media as a nasal decongestant.

Pharmacology

Oxymetazoline Hydrochloride is a sympathomimetic amine that is derived from imidazoline. It acts as a direct agonist on -adrenoceptors but not on -adrenoceptors. When applied topically to the nasal mucosa, it causes a quick and long-acting vasoconstriction of the arterioles, which reduces blood flow and reduces mucosal edema. As a result, the airway's potency improves, and the nasal sinuses drain more effectively.

Dosage and Administration

Oxymetazoline nasal spray-

Adults and children (6 years of age and older): 2 or 3 sprays in each nostril twice daily for 3-5 days.

Elderly: There is no need for dosage reduction in the elderly for nasal administration.

Children below 6 years of age: It is not suitable for children below 6 years of age.

Oxymetazoline nasal drop-

Adults & children 6 years of age: 2-3 drops of 0.05% Nasal Drops in each nostril twice daily in the morning and evening.

Children 2-5 years of age: 2-3 drops of 0.025% Nasal Drops in each nostril twice daily in the morning and evening

How to use the Nasal Spray-

• Shake the bottle gently and remove the dust cover.
• Hold the spray with your forefinger and middle finger on either side of the nozzle and your thumb underneath the bottle. Press down until a fine spray appears. If using for the first time or if you have not used it for a week or more, press the nasal applicator several times until a fine moist comes out from the container.
• Gently blow the nose to clear the nostrils.
• Close one nostril and carefully insert the nasal applicator into the open nostril. Tilt your head forward slightly and keep the spray upright. Breathe in through your nose and while breathing in, press the white-collar of nasal applicator firmly down once to release a spray.
• Breathe out through your mouth.
• Repeat the above steps in the same/ other nostril for consecutive doses.
• Cleaning: The nasal spray should be cleaned at least once a week. The procedures are as follows-
• Remove the dust cover.
• Gently pull off the nasal applicator.
• Wash the applicator and dust cover in warm water.
• Shake off the excess water and leave to dry in a normal place. Avoid to apply additional heat.
• Gently push the applicator back on the top of the bottle and re-fix the dust cover.

Interaction

Patients taking MAO inhibitors or those who have just stopped taking them should not use Oxymetazoline Hydrochloride Nasal Preparation.

Contraindications

Cardiovascular illness, hyperthyroidism, prostatic enlargement, angle closure glaucoma, and intolerance to any of the components are all contraindications.

Side Effects

It can cause local irritation and dryness of the mouth and throat on occasion. Burning, stinging, sneezing, or an increase in nasal discharge may occur for a short time.

Pregnancy & Lactation

Although the safety of Oxymetazoline Hydrochloride Nasal Spray during pregnancy and breastfeeding has not been proved, it is not believed to pose a risk during these times.

Precautions & Warnings

Keep your distance from the eyes. Without medical advice, the spray should not be used for more than seven days. Nasal congestion may reoccur or worsen if used frequently or for an extended period of time.

Therapeutic Class

Nasal antihistamines, nasal decongestants, and other nasal treatments are available.

Storage Conditions

Protect from light and store below 30° C in a dry area. Do not freeze or refrigerate. Keep out of children's reach.

Pharmaceutical Name

Aristopharma Ltd.