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Cefaten Powder for Suspension 100 ml bottle


  • 775.00Tk.



Indications

Ceftibuten is indicated for the treatment of individuals with mild-to-moderate infections caused by susceptible strains of the designated microorganisms in the specific conditions listed below.
  • Acute Bacterial Exacerbations of Chronic Bronchitis: Due to Haemophilus influenzae (including β-lactamase producing strains), Moraxella catarrhalis (including (β-lactamase producing strains), or Streptococcus pneumoniae (penicillin-susceptible strains only).
  • Acute Bacterial Otitis Media: Due to Haemophilus influenzae (including β-lactamase producing strains), Moraxella catarrhalis (including β-lactamase producing strains) or Streptococcus pyogenes.
  • Pharyngitis and Tonsillitis: Due to Streptococcus pyogenes.

Pharmacology

Ceftibuten is the dihydrate salt of Ceftibuten, is a semi-synthetic Cephalosporin antibiotic for oral administration. Ceftibuten exerts its bactericidal action by binding to essential target proteins of the bacterial cell wall. This binding leads to inhibition of cell-wall synthesis.

Dosage & Administration

Otitis Media-
  • Adult Dosage: 400 mg orally every 24 hours for 10 days
  • Pediatric Dosage: >6 months: 9 mg/kg/day (maximum 400 mg) every 24 hours for 10 days
Tonsillitis/Pharyngitis-
  • Adult Dosage: 400 mg orally every 24 hours for 10 days
  • Pediatric Dosage: >6 months: 9 mg/kg/day (maximum 400 mg) every 24 hours for 10 days
Bronchitis-
  • Adult Dosage: 400 mg orally every 24 hours for 10 days
  • Pediatric Dosage: >12 years: 400 mg orally every 24 hours for 10 days
Cystitis-
  • Adult Dosage: 400 mg orally every 24 hours for 7 days
  • Pediatric Dosage: >12 years: 400 mg orally every 24 hours for 7 days
Pneumonia-
  • Adult Dosage: 200 mg orally every 12 hours for 7 to 14 days
  • Pediatric Dosage: >12 years: 200 mg orally every 12 hours for 7 to 14 days
Sinusitis-
  • Adult Dosage: 400 mg orally every 24 hours for 10 to 14 days
  • Pediatric Dosage: >12 years: 400 mg orally every 24 hours for 10 to 14 days
Urinary tract Infection-
  • Adult Dosage: 400 mg orally every 24 hours for 10 days
  • Pediatric Dosage: >6 months: 9 mg/kg/day (maximum 400 mg) every 24 hours for 10 days

Interaction

Theophylline & Antacid do not alter the pharmacokinetic profile of Ceftibuten. Ranitidine increases the Cmax & AUC of Ceftibuten.

Contraindications

Ceftibuten is contraindicated in patients with known allergy to the cephalosporin group of antibiotics.

Side Effects

Nausea, headache, diarrhea, dyspepsia, dizziness, abdominal pain, vomiting.

Tags: Cefaten Powder for Suspension 100 ml bottle