Dorenta Syrup 100 ml bottle
- Brand:Eskayef Pharmaceuticals Ltd
- Product Code: Diphenhydramine Hydrochloride 10 mg/5 ml
- Availability: In Stock
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40.00Tk.
Indications
Diphenhydramine is indicated for the treatment of followings:
- Seasonal, perennial, vasomotor rhinitis
- Urticaria, angioneurotic oedema, anaphylaxis
- Pruiritic conditions
- Premedication for emesis and motion sickness
- Miscellaneous like meniere's disease and parkinsonism
Pharmacology
Diphenhydramine is an antihistamine with anticholinergic and sedative effects. It competes with histamine for H1-receptor sites on effector cells in the GI tract, blood vessels and respiratory tract.
Dosage & Administration
Adult-
- Most allergic conditions: 25-50 mg three times a day with a further 50 mg at night.
- 1 to 5 years of age: 5 mg i.e., 2.5 ml of elixir 4 times a day
- More than 6 years of age: 10 mg i.e. 5 ml of elixir 4 times a day
Interaction
Diphenhydramine administration significantly reduces the absorption of the antituberculous agent para-aminosalicyclic acid (PAS) from the gastrointestinal tract. CNS depressants may potentiate the sedative action of Diphenhydramine. Anticholinergic drugs may potentiate Diphenhydramine’s anticholinergic side effects.
Contraindications
Known hypersensitivity to Diphenhydramine Hydrochloride, Ammonium chloride is contra-indicated in presence of impaired hepatic or renal function.
Side Effects
Side effect includes sedation, dizziness, tinnitus, fatigue, ataxia, blurred vision, diplopia, euphoria, and epigastric discomfort.