Ebasten 10 Tablet
- Brand:ACI Limited
- Product Code: Ebastine 10mg
- Availability: In Stock
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7.60Tk.
Indication
Ebasten is used to treat the symptoms of seasonal and permanent allergic rhinitis, as well as chronic idiopathic urticaria.
Pharmacology
Ebastine is a long-acting, selective histamine H1 receptor antagonist. Peripheral receptor blockade remained stable after repeated treatments. After oral administration, ebastine is easily absorbed and undergoes significant first-pass metabolism. Cabostin is a pharmacologically active acid metabolite, which is almost completely converted from ebastine.
Dosage & Administration
Tablet:
- Adults (more than 12 years of age): 10 mg (one tablet) once daily.
- Children (6-12 years of age): 5 mg (half tablet) once daily.
Syrup:
- Children (2-5 years of age): 2.5 ml once daily (upto 5 ml in severe cases such as Perennial Allergic Rhinitis).
- Children (6-12 years of age): 5 ml once daily (upto 10 ml in severe cases such as Perennial Allergic Rhinitis).
Ebastine may be taken with or without food.
Interaction
Concomitant use of ketoconazole, itraconazole, clarithromycin or erythromycin may increase plasma levels of Ebastine and cause QTc interval prolongation. The sedation effect of alcohol and diazepam may be enhanced.
Contraindications
Ebastine is contraindicated in patients with known hypersensitivity to Ebastine or to any of the components of this preparation.
Side Effects
The most common side effects are headache, dry mouth and drowsiness. Less commonly reported side effects include pharyngitis, abdominal pain, dyspepsia, asthenia, epistaxis, rhinitis, sinusitis, nausea and insomnia.
Pregnancy & Lactation
Pregnancy: Ebastine is pregnancy category B. Ebastine should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.
Lactation: It is not known whether Ebastine is excreted in human milk. As a precautionary measure, it is preferable to avoid the use of Ebastine during lactation.
Precautions & Warnings
Caution is advised when used in QTc interval prolongation, hypokalemia, treatment with any medicine known to produce an increase in QTc interval or inhibit CYP3A4 enzyme systems such as azole antifungals, macrolide antibiotics and a type of medicine used to treat tuberculosis (e.g. rifampicin).
Therapeutic Class
Antihistamines that don't make you sleepy.
Storage Conditions
Store below 30°C at a cool and dry place, away from light. Keep out of reach of children
Pharmaceutical Name
ACI Limited
Tags: Ebasten 10 Tablet